|  Help  |  About  |  Contact Us

Allele : Proc<tm1Fjc> protein C; targeted mutation 1, Francis J Castellino

Primary Identifier  MGI:2183063 Allele Type  Targeted
Attribute String  Null/knockout Gene  Proc
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  Exons 2 through 9, containing the entire coding region, were deleted by the insertion of a neomycin selection cassette. Northern blot analysis showed that transcript encoded by the endogenous allele was absent in homozygous mutant embryos. Assays of plasma obtained from homozygous mutant mice showed a lack of amidolytic activity.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • PC<->,
  • PC<->
Quick Links:
 
Quick Links:
 

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

12 Publication categories