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Allele : Ucp3<tm1Rei> uncoupling protein 3 (mitochondrial, proton carrier); targeted mutation 1, Marc L Reitman

Primary Identifier  MGI:2183202 Allele Type  Targeted
Attribute String  Null/knockout Gene  Ucp3
Transmission  Germline Strain of Origin  129S6/SvEvTac
Is Recombinase  false Is Wild Type  false
molecularNote  4.0 kb of sequence, including the first coding exon (exon 2), was deleted and replaced with a neomycin selection cassette. Northern blot and RT-PCR analyses detected aberrantly spliced transcript, in which exon 1 had spliced directly to exon 3, in homozygous mutant mice. Protein encoded from the aberrant transcript was undetected via Western blot analysis.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Ucp3 (-),
  • Ucp3 (-)
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

22 Publication categories

Trail: Allele