| Primary Identifier | MGI:2183226 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Tnfrsf11a |
| Transmission | Germline | Strain of Origin | 129X1/SvJ |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A portion of exon 2 and all of exon 3 was replaced with a neomycin selection cassette. The deleted region encoded approximately one and one half of the amino-terminal TNFR-like cysteine-rich domain, comprised of residues 34 through 96. Northern blot analysis confirmed the absence of normal transcript, while the results of a Western blot analysis of intestinal lysates using antibodies raised against the extracellular domain of the endogenous protien indicated a lack of protein. |
