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Allele : Akr1b1<tm1Skc> aldo-keto reductase family 1 member B; targeted mutation 1, Sookja K Chung

Primary Identifier  MGI:2183239 Allele Type  Targeted
Attribute String  Null/knockout Gene  Akr1b1
Transmission  Germline Strain of Origin  129S7/SvEvBrd-Hprt1<b-m2>
Is Recombinase  false Is Wild Type  false
molecularNote  2.7kb of sequence, encompassing a portion of exon 5 and all of exons 6, 7, and 8, was replaced by a neomycin selection cassette. The absence of transcript and protein in homozygous mutant mice was determined via Northern blot and Western blot analyses of various tissues.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Aldor1<->,
  • AR<->,
  • AR-KO,
  • Aldor1<->,
  • AR-KO,
  • AR<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

23 Publication categories