| Primary Identifier | MGI:2183276 | Allele Type | Targeted |
| Attribute String | Null/knockout, Reporter | Gene | Nkx3-2 |
| Transmission | Germline | Strain of Origin | 129S4/SvJae |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | The entire coding region, spanning exons 1 and 2, was replaced with a cassette containing an NLS-lacZ gene and a floxed neo gene. The cassette was inserted at the translational start codon, which enabled expression of beta-galactosidase from the endogenous promoter. Northern blot analysis of total RNA obtained from homozygous mutant embryos showed a lack of transcript. |
