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Allele : Mapk9<tm1Mka> mitogen-activated protein kinase 9; targeted mutation 1, Michael Karin

Primary Identifier  MGI:2183601 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Mapk9
Transmission  Germline Strain of Origin  129/Sv
Is Recombinase  false Is Wild Type  false
description  ES cell line = D3 (129S2/SvPas) or R1 ((129X1/SvJ x 129S1/Sv)F1-Kitl+).
molecularNote  Part of exon 1 and exon 2 were replaced with a lacZ-neo cassette via homologous recombination resulting in the in frame fusion of the first 32 amino acids with lacZ and deletion of part of the kinase domain. Northern blot analysis of homozygous mutant animals did not detect either full length or truncated transcripts. Western blot analysis of mouse embryonic fibroblasts cultured from homozygous mutants did not detect either isoform (46 kDa, 55kDa) of protein product.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • JNK2<->,
  • JNK2<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

37 Publication categories