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Allele : Gna12<tm1Citb> guanine nucleotide binding protein, alpha 12; targeted mutation 1, California Institute of Technology - Biology

Primary Identifier  MGI:2183606 Allele Type  Targeted
Attribute String  Null/knockout Gene  Gna12
Transmission  Germline Strain of Origin  129S1/Sv-Oca2<+> Tyr<+> Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  Approximately one-third of the coding sequence was replaced with a neomycin selection cassette into exon 4. A trunctated transcript was identified in homozygous mutant mice by Northern blot and RT-PCR analyses. Western blot analysis, using antibodies directed against the amino and carboxy termini, showed the absence of protein.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Galpha12-,
  • Galpha12-,
  • Gna12-,
  • Gna12-
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

41 Publication categories