| Primary Identifier | MGI:2183607 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Icmt |
| Transmission | Germline | Strain of Origin | 129S/SvEv |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A floxed region containing exons 2 through 4 was excised via the in vitro expression of cre recombinase. The deleted sequence encoded amino acids 65 through 224. Northern blot analysis of heterozygous mice showed an approximately 50% reduction in transcript levels, whereas transcript was undetected in homozygous mutant embryos by RT-PCR analysis. |
