| Primary Identifier | MGI:2183718 | Allele Type | Transgenic |
| Attribute String | Humanized sequence, Inserted expressed sequence | Gene | Tg(SOD1*G93A)2Gur |
| Strain of Origin | (C57BL/6 x SJL)F1 | Is Recombinase | false |
| Is Wild Type | false |
| description | This is the original high copy number line, G1, reported in J:32556. Subsequently, the Tg(SOD1*G93A)1Gur line, which has a 40% greater copy number was derived from the original founder G1 and reported in J:76718. |
| molecularNote | The transgene construct consists of a human SOD1 gene carrying a glycine to alanine substitution at position 93 (G93A). The G93A mutation does not alter the activity of the protein. Northern blot and Western blot confirmed the expression of the human transgene in transgenic animals. |
