| Primary Identifier | MGI:2183755 | Allele Type | Transgenic |
| Attribute String | Inserted expressed sequence | Gene | Tg(Pmp22)247Ueli |
| Strain of Origin | (C57BL/6 x C3H)F1 | Is Recombinase | false |
| Is Wild Type | false |
| description | Founder 247 is representative of 2 founders (247 and 249) carrying approximately 30 copies of the transgene and exhibiting similar phenotypes. Transgenic animals display slight shivering at 2 weeks of age most apparent in the head. At 4 weeks the animals exhibit unsteady gait and progress to muscle atrophy at 2-3 months leading eventually to hind limb paralysis. |
| molecularNote | The entire mouse Pmp22 gene including 7 kb of upstream and 4 kb of downstream sequences was used as the transgene. |
