Primary Identifier | MGI:2383982 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Fcer1a |
Transmission | Germline | Strain of Origin | 129 |
Is Recombinase | false | Is Wild Type | false |
description | ES cell line = D3 (129S2/SvPas) or E14TG2a (129P2/OlaHsd). |
molecularNote | Exon 4, encoding an immunoglobulin domain, was disrupted by the insertion of a neomycin selection cassette. The absence of a functional encoded protein on the cell surface was determined by fluorescence activated cell sorting analysis of bone marrow mast cells obtained from homozygous mutant mice. |