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Allele : Irak1<tm1Jth> interleukin-1 receptor-associated kinase 1; targeted mutation 1, James A Thomas

Primary Identifier  MGI:2384212 Allele Type  Targeted
Attribute String  Null/knockout Gene  Irak1
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
description  ES cell line = E1.1C.
molecularNote  7.0 kb of sequence was replaced by the insertion of neomycin selection cassette. The deleted region included 3.5 kb of the upstream regulatory region, all of exons 1 through 8, and a portion of exon 9. Western blot analysis of mouse embryonic fibroblasts showed an absence of encoded protein in homozygous mutant mice.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • IRAK-1<->,
  • IRAK-1<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

30 Publication categories