| Primary Identifier | MGI:2183789 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Kif3c |
| Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A 4.5 kb region of the gene including exon 1, which encode amino acids 1-518 including the whole motor region and half of the alpha-helical coiled coil domains, was replaced with a PGK-neo cassette via homologous recombination. Western blot analyis of brain lysates using antibodies directed against the C-terminus of the protein confirmed the absence of gene expression in homozygous mutant animals. |
