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Allele : Tg(APOB)1Rub transgene insertion 1, Edward M Rubin

Primary Identifier  MGI:2183816 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(APOB)1Rub
Strain of Origin  FVB Is Recombinase  false
Is Wild Type  false
molecularNote  The human APOB gene (~19 kb of genomic sequence 5' to the translational start site of the gene and ~14kb of genomic sequence 3' to the transcription termination site) was introduced into fertilized FVB mouse embryos. Multiple lines were generated, ranging in copy number from 1 to 11 for the human gene, by Southern blot. This transgene is the low-expressing line, with an estimated one copy of the APOB gene in liver of these mice.
  • mutations:
  • Insertion
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

2 Publication categories