| Primary Identifier | MGI:2383955 | Allele Type | Transgenic |
| Attribute String | Inserted expressed sequence | Gene | Tg(Fabpl-RAC1-Q61L)1Jig |
| Transmission | Chimeric | Strain of Origin | 129S2/SvPas |
| Is Recombinase | false | Is Wild Type | false |
| description | Chimeric animals generated from the transgene died within a day after birth. |
| molecularNote | A human RAC1 gene carrying a constitutive glutamine to leucine mutation at amino acid 61 was used for the transgene. Nucleotides -596 to +21 from Fabpl were used to drive expression of the transgene in intestinal epithelium. Western blot analysis confirmed the expression of the transgene in the small intestines of E18.5 chimeric embryos. |
