| Primary Identifier | MGI:2384142 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Rorc |
| Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A 200 bp fragment of the gene containing the exon encoding the DNA-binding domain was replaced with a neomycin resistance cassette via homologous recombination. Gene expression was undetectable in various tissues from homozygous mutant animals as determined by Northern blot analysis using a full-length cDNA probe. Western blot analysis did not detect protein expression in thymus of homozygous mutants. |
