Primary Identifier | MGI:2384496 | Allele Type | Targeted |
Attribute String | Null/knockout, Reporter | Gene | Etv1 |
Transmission | Germline | Strain of Origin | 129S1/Sv-Oca2<+> Tyr<+> Kitl<+> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A cassette containing nls-lacZ was inserted in frame into exon 2. While normal protein was undetected in homozygous mutant embryos at E13.5, approximately 5% of dorsal root ganglion neurons showed reactivity after E15. The authors believe the expression to be that of inactive protein lacking the activation domain. |