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Allele : Tg(Fabpl-CTNNB1)1Jig transgene insertion 1, Jeffrey I Gordon
Primary Identifier  MGI:2383988 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(Fabpl-CTNNB1)1Jig
Transmission  Chimeric Strain of Origin  129S2/SvPas
Is Recombinase  false Is Wild Type  false
molecularNote  A human CTNNB1 gene deleted for 89 N-terminal amino acids was used for the transgene. Nucleotides -596 to +21 from Fabpl were used to drive expression of the transgene in intestinal epithelium. RT-PCR analysis confirmed the expression of the transgene. Western blot of total jejunal proteins and immunohistochemistry of jejunal sections confirmed transgene protein product in transgenic animals.
  • mutations:
  • Insertion
  • synonyms:
  • deltaN89beta-catenin,
  • deltaN89beta-catenin
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories





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