| Primary Identifier | MGI:2384015 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | F11 |
| Transmission | Germline | Strain of Origin | 129X1/SvJ |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Exon 5, encoding a portion of the second apple domain, was disrupted by the insertion of a neomycin selection cassette. Sequence analysis showed that a frameshift mutation would be generated if exon 4 were to splice to exon 6 due to the excision of the disrupted exon 5. Transcript was undetected in homozygous mutant mice via Northern blot and RT-PCR analyses of total hepatic RNA. |
