| Primary Identifier | MGI:2384092 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Mag |
| Transmission | Germline | Strain of Origin | 129S2/SvPas |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | The gene was disrupted by insertion of a PGK-neo cassette into exon 5 via homologous recombination. Absence of gene expression was confirmed by Western blot analysis of brain proteins from 26-day-old homozygous mutant animals. Immunohistochemical analysis of sciatic and optic nerve sections from 8-week-old homozygous mutants also failed to detect protein. |