Primary Identifier | MGI:2384616 | Allele Type | Transgenic |
Attribute String | Humanized sequence, Inserted expressed sequence | Gene | Tg(KRT5-E2F1)2Dgj |
Strain of Origin | (C57BL/6 x SJL/J)F2 | Is Recombinase | false |
Is Wild Type | false |
molecularNote | Human E2F1 cDNA was adjoined to the bovine keratin promoter. Overexpression of the transgene in epidermal cells was confirmed by immunohistochemical analysis. Western blot analysis showed that the level of transgenic protein was 47 fold greater than that of the endogenous protein. |