Primary Identifier | MGI:2384629 | Allele Type | Targeted |
Attribute String | Conditional ready, No functional change | Gene | H2-Ab1 |
Transmission | Germline | Strain of Origin | 129X1/SvJ |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A construct, in which the first coding exon was flanked by an upstream floxed neo cassette and a downstream loxP site, was integrated via homologous recombination. Flow cytometric analysis of splenocytes showed that the insertion of the loxP sites and neo cassette did not affect MHC-II surface expression. |