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Allele : Mdm2<tm2.1Glo> transformed mouse 3T3 cell double minute 2; targeted mutation 2.1, Guillermina Lozano

Primary Identifier  MGI:2385439 Allele Type  Targeted
Attribute String  Conditional ready, No functional change Gene  Mdm2
Transmission  Germline Strain of Origin  129S7/SvEvBrd-Hprt1<+>
Is Recombinase  false Is Wild Type  false
molecularNote  The floxed neo cassette of Mdm2tm2Glo was excised from intron 6 via germline expression of cre recombinase. Exons 5 and 6, encoding most of the Trp53-binding domain (residues 53 through 113), were left flanked by single loxP sites in introns 4 and 6.
  • mutations:
  • Insertion
  • synonyms:
  • FM,
  • FM
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

42 Publication categories