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Allele : Tg(TLK2mHEL)2Ccg transgene insertion 2, Christopher C Goodnow

Primary Identifier  MGI:2385453 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(TLK2mHEL)2Ccg
Inheritance Mode  Not Specified Strain of Origin  C57BL/6JSfd
Is Recombinase  false Is Wild Type  false
molecularNote  A genomic fragment containing the coding exons of the chicken lysozyme gene (also known as hen egg lysozyme, HEL) was linked to a 3.3kb fragment of the rat thyroglobulin promoter and to the mouse H2-Kb transmembrane sequence (which included the extracellular spacer sequence, transmembrane segment, and cytoplasmic tail). Thyroids from mice carrying the transgene showed expression of chicken lysozyme by Western blot; spleen, islets, and thymus did not.
  • mutations:
  • Insertion
  • synonyms:
  • TLK-2,
  • thyroHEL,
  • TLK-2,
  • thyroHEL
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

4 Publication categories