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Allele : Nras<tm1Rak> neuroblastoma ras oncogene; targeted mutation 1, Raju Kucherlapati

Primary Identifier  MGI:2385944 Allele Type  Targeted
Attribute String  Null/knockout Gene  Nras
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  2.2 kb of sequence from the 3' portion of exon 2 were replaced with a neomycin selection cassette via homologous recombination. The deleted sequence encoded two thirds of the carboxy terminal amino acids. Protein was undetected by Western blot analysis of extracts obtained from the lungs of homozygous mutant mice.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • N-ras-,
  • N-ras-
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

24 Publication categories