Primary Identifier | MGI:2385944 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Nras |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
Is Recombinase | false | Is Wild Type | false |
molecularNote | 2.2 kb of sequence from the 3' portion of exon 2 were replaced with a neomycin selection cassette via homologous recombination. The deleted sequence encoded two thirds of the carboxy terminal amino acids. Protein was undetected by Western blot analysis of extracts obtained from the lungs of homozygous mutant mice. |