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Allele : Enpp1<tm1Gdg> ectonucleotide pyrophosphatase/phosphodiesterase 1; targeted mutation 1, J W Goding

Primary Identifier  MGI:2385534 Allele Type  Targeted
Attribute String  Null/knockout Gene  Enpp1
Transmission  Germline Strain of Origin  129S1/Sv-Oca2<+> Tyr<+> Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 9 was disrupted by the insertion of a neomycin selection cassette. RT-PCR analysis of total renal RNA showed the presence of an elongated transcript in homozygous mice, putatively resulting from a cryptic splice site within the neo transgene. Immunohistochemical analysis of epididymal sections showed an absence of encoded protein in homozygous mutant mice.
  • mutations:
  • Insertion
  • synonyms:
  • PC-1-,
  • Enpp1<->,
  • PC-1-,
  • Enpp1<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

22 Publication categories