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Allele : Pik3cd<tm1Bvan> phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta; targeted mutation 1, Bart Vanhaesebroeck

Primary Identifier  MGI:2385595 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Pik3cd
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  A point mutation was introduced via homologous recombination altering the DFG motif in the C-terminal kinase domain to AFG, and a myc tag and floxed -neo-lacZ cassette were inserted after the stop codon. Southern blot confirmed the presence of the mutation in chimeric animals.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • p110delta<lz>,
  • p110delta<lz>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

5 Publication categories