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Allele : Myl2<tm1(cre)Krc> myosin, light polypeptide 2, regulatory, cardiac, slow; targeted mutation 1, Kenneth R Chien

Primary Identifier  MGI:2385922 Allele Type  Targeted
Attribute String  Recombinase Gene  Myl2
Transmission  Germline Strain of Origin  129S4/SvJae
Is Recombinase  true Is Wild Type  false
molecularNote  Part of exon 1 and all of exon 2 were replaced with a cre gene and a floxed PGK-neo-tk cassette via homologous recombination. Western blot analysis showed that homozygous embryos did not express Myl2 protein product. The knocked in cre gene is expressed by the Myl2 promoter in ventricular tissue starting at day E7.5.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • MLC2vcreKI,
  • MLC2v-cre,
  • Mlc2v-cre,
  • MLC2vcreKI,
  • MLC2v-cre,
  • MLC-2v -,
  • Mlc2v-cre,
  • MLC-2v -
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

3 Carried By

1 Driven By

141 Publication categories