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Allele : Nfe2l2<tm1Ywk> nuclear factor, erythroid derived 2, like 2; targeted mutation 1, Yuet Wai Kan

Primary Identifier  MGI:2385926 Allele Type  Targeted
Attribute String  Null/knockout Gene  Nfe2l2
Transmission  Germline Strain of Origin  129X1/SvJ
Is Recombinase  false Is Wild Type  false
molecularNote  A 4.2 kb segment, includind part of exon 4 and all of exon 5, was replaced by an in-frame lacZ gene followed by a neomycin selection cassette. Northern blot analysis on RNA derived from various tissues confirmed that a fusion transcript was detectable in intestine of homozygous mice, but no wild-type transcript was detectable in any tissue. However, no fusion protein was detected by histochemical staining in any adult tissue.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Nrf2-,
  • NRF2-,
  • Nrf2 KO,
  • NRF2-,
  • Nrf2-,
  • Nrf2 KO
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

3 Carried By

0 Driven By

237 Publication categories