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Allele : Mmp12<tm1Sds> matrix metallopeptidase 12; targeted mutation 1, Steven D Shapiro

Primary Identifier  MGI:2386174 Allele Type  Targeted
Attribute String  Null/knockout Gene  Mmp12
Transmission  Germline Strain of Origin  129X1/SvJ
Is Recombinase  false Is Wild Type  false
molecularNote  The gene was disrupted by replacement of the majority of exon 2 with a PGK-neo cassette via homologous recombination. Gene transcription and protein production was absent in homozygous mutant animals as demonstrated by Northern and Western blot analysis of peritoneal macrophages and peritoneal fluid.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • MMP-12-,
  • MME-,
  • Mmp12<->,
  • Mmp12<->,
  • MMP-12-,
  • MME-
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

74 Publication categories