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Allele : Pdcd1<tm1Hon> programmed cell death 1; targeted mutation 1, Tasuku Honjo

Primary Identifier  MGI:2386184 Allele Type  Targeted
Attribute String  Null/knockout Gene  Pdcd1
Transmission  Germline Strain of Origin  129S2/SvPas
Is Recombinase  false Is Wild Type  false
molecularNote  A region encoding both transmembrane and cytoplasmic domains was deleted by the replacement of sequence extending from within exon 3 through a portion of exon 4 with a neomycin selection cassette. Flow cytometric analysis of cultured cells derived from homozygous mutant mice showed a lack of protein expression on the cell surface.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • PD-1<->,
  • PD-1<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

10 Carried By

0 Driven By

137 Publication categories