| Primary Identifier | MGI:2385836 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Mpo |
| Transmission | Germline | Strain of Origin | 129X1/SvJ |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Exon 7, which includes sequence involved in heme binding, was disrupted by the insertion of a neomycin selection cassette and a premature stop codon, which precludes the translation of sequence encoding the heavy chain. Northern and Western blot analyses of bone marrow confirmed the absence of transcript and protein in homozygous mutant mice. |
