Primary Identifier | MGI:2386436 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Ackr1 |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A 2.2 kb region of the gene containing the 5' untranslated region and exons 1-2 was deleted and replaced with a neomycin resistance cassette via homologous recombination. Homozygous mutant animals lacked gene expression as determined by Northern blot analysis of brain and spleen RNA. |