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Allele : Rpgr<tm1Tili> retinitis pigmentosa GTPase regulator; targeted mutation 1, Tiansen Li

Primary Identifier  MGI:2386674 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Rpgr
Transmission  Germline Strain of Origin  129S4/SvJae
Is Recombinase  false Is Wild Type  false
molecularNote  Part of exon 4 through part of exon 6 was replaced with a promoter-less lacZ-neo cassette via homologous recombination. Northern blot analysis using a full length cDNA probe did not detect gene expression in brains from homozygous mutant animals. RT-PCR analysis also did not detect gene transcripts. Western blot analysis of protein from brain, retina, and testis confirmed the null allele.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • RPGR-,
  • RPGR-
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

20 Publication categories