Primary Identifier | MGI:2386674 | Allele Type | Targeted |
Attribute String | Null/knockout, Reporter | Gene | Rpgr |
Transmission | Germline | Strain of Origin | 129S4/SvJae |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Part of exon 4 through part of exon 6 was replaced with a promoter-less lacZ-neo cassette via homologous recombination. Northern blot analysis using a full length cDNA probe did not detect gene expression in brains from homozygous mutant animals. RT-PCR analysis also did not detect gene transcripts. Western blot analysis of protein from brain, retina, and testis confirmed the null allele. |