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Allele : Satb1<tm1Kos> special AT-rich sequence binding protein 1; targeted mutation 1, Terumi Kohwi-Shigematsu

Primary Identifier  MGI:2386676 Allele Type  Targeted
Attribute String  Null/knockout Gene  Satb1
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  A 10.9 kb region containing exons 1 through 5 was replaced by a neomycin selection cassette inserted at the endogenous locus via homologous recombination. The deleted exons encoded 213 amino acids, including the intitiator methionine. RT-PCR and Western blot analyses of thymus extracts showed an absence of endogenous transcript and protein in homozygous mutant mice.
  • mutations:
  • Insertion,
  • Intragenic deletion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

12 Publication categories