| Primary Identifier | MGI:2386676 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Satb1 |
| Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A 10.9 kb region containing exons 1 through 5 was replaced by a neomycin selection cassette inserted at the endogenous locus via homologous recombination. The deleted exons encoded 213 amino acids, including the intitiator methionine. RT-PCR and Western blot analyses of thymus extracts showed an absence of endogenous transcript and protein in homozygous mutant mice. |