Primary Identifier | MGI:2386101 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Pou2af1 |
Transmission | Germline | Strain of Origin | C57BL/6 |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Exons 2 through 4, encompassing approximately 60% of the coding region, were replaced with a neomycin selection cassette. The deleted region encoded the amino terminal activation domain and a portion of the carboxy terminal domain. RT-PCR analysis of total spleen RNA showed an absence of transcript in homozygous mutant mice. |