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Allele : Rarb<tm2Ipc> retinoic acid receptor, beta; targeted mutation 2, Pierre Chambon

Primary Identifier  MGI:2386108 Allele Type  Targeted
Attribute String  Conditional ready, No functional change Gene  Rarb
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  Exons 9 and 10, which encode amino acids 263 through 384 encompassing most of the ligand binding domain, were left flanked by loxP sites after the in vitro cre-mediated excision of a selection cassette. Both isoforms produced by the endogenous gene were detected in homozygous mutant mice, verifying that the presence of the loxP sites did not affect gene function.
  • mutations:
  • Insertion
  • synonyms:
  • RARbeta<L2>,
  • RARbeta<L2>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

15 Publication categories