Primary Identifier | MGI:2386108 | Allele Type | Targeted |
Attribute String | Conditional ready, No functional change | Gene | Rarb |
Transmission | Germline | Strain of Origin | Not Specified |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Exons 9 and 10, which encode amino acids 263 through 384 encompassing most of the ligand binding domain, were left flanked by loxP sites after the in vitro cre-mediated excision of a selection cassette. Both isoforms produced by the endogenous gene were detected in homozygous mutant mice, verifying that the presence of the loxP sites did not affect gene function. |