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Allele : Rarb<tm2.1Ipc> retinoic acid receptor, beta; targeted mutation 2.1, Pierre Chambon

Primary Identifier  MGI:2386109 Allele Type  Targeted
Attribute String  Null/knockout Gene  Rarb
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  The floxed fragment containing exons 9 and and 10 was excised from Rarbtm2Ipc by the ubiquitous in vivo expression of cre recombinase. The deletion eliminated the majority of the ligand binding domain and introduced a frameshift mutation. Neither isoform produced by the endogenous gene was detected in homozygous mutant mice via immunoblot analysis.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • RARbeta<L->,
  • RARbeta<L->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

5 Publication categories