Primary Identifier | MGI:2386246 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Mmp14 |
Transmission | Germline | Strain of Origin | 129X1/SvJ |
Is Recombinase | false | Is Wild Type | false |
molecularNote | 0.5 kb of the gene including part of exon 4 was replaced with a neomycin resistance cassette via homologous recombination. Northern blot analysis of lung and heart from homozygous mutant mice confirmed the absence of gene expression. |