Primary Identifier | MGI:2386252 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Mmp2 |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
Is Recombinase | false | Is Wild Type | false |
molecularNote | 5.9 kb of the gene including exon 1 was replaced with a PGK-neo cassette via homologous recombination. Absence of protein activity in the brain, lungs, and kidneys of homozygous mutant animals was confirmed by gelatin zymography. |