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Allele : Mmp3<tm1Mrl> matrix metallopeptidase 3; targeted mutation 1, Merck Research Laboratory

Primary Identifier  MGI:2386262 Allele Type  Targeted
Attribute String  Null/knockout Gene  Mmp3
Transmission  Germline Strain of Origin  129S7/SvEvBrd-Hprt1<b-m2>
Is Recombinase  false Is Wild Type  false
molecularNote  The zinc-binding site was deleted by replacement of partial exon 3 and entire exon 4 with a neomycin resistance cassette via homologous recombination. Inactivation of the gene was confirmed via Northern blot analysis of Il1a- and Il1b-stimulated primary embryonic fibroblasts derived from homozygous mutant animals.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • MMP-3 -,
  • SLN1-deficient,
  • MMP-3 -,
  • SLN1-deficient
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

44 Publication categories