| Primary Identifier | MGI:2386270 | Allele Type | Targeted |
| Gene | Tyrobp | Transmission | Germline |
| Strain of Origin | 129P2/OlaHsd | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | Sequence encoding conserved amino acids 75 through 86 (YSDLNTQRQYR) of the immunoreceptor tyrosine-based activation motif (ITAM) was replaced with a vector containing a floxed neo cassette followed by sequence encoding a putatively non-functional 15 amino acid peptide (GLQEFIEDEKKKRNSI). Mice carrying this allele were bred with transgenic mice expressing cre via the ubiquitous CMV promoter to generate Tyrobptm1.1Viv. |
