Primary Identifier | MGI:2386271 | Allele Type | Targeted |
Gene | Tyrobp | Transmission | Germline |
Strain of Origin | 129P2/OlaHsd | Is Recombinase | false |
Is Wild Type | false |
molecularNote | The floxed neo cassette was excised from Tyrobptm1Viv via ubiquitous in vivo expression of cre recombinase. RT-PCR analysis showed that the sequence inserted to replace a region encoding a portion of the immunoreceptor tyrosine-based activation motif (ITAM) was left intact along with a single upstream loxP site. |