| Primary Identifier | MGI:2386369 | Allele Type | Transgenic |
| Attribute String | Inserted expressed sequence | Gene | Tg(BLG-Mdm2)1Caf |
| Strain of Origin | (C57BL/6 x C3H)F2 | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | A full-length Mdm2 coding sequence (including introns 7 and 8) fused to the bovine beta-lactoglobulin (BLG) promoter, active in mammary glands, was used as the transgene. RNase protection assay of total RNA from mid-lactation mammary glands confirmed expression of the transgene intransgenic animals and detected both spliced and unspliced forms. Overexpression of the transgene was estimated to be 10-30 times that of the endogenous gene. |
