| Primary Identifier | MGI:2386445 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Myh10 |
| Transmission | Germline | Strain of Origin | 129S4/SvJae |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | The gene was disrupted by insertion of a PGK-neo cassette into exon 2 just downstream of the translation initiation codon via homologous recombination. Northern blot analysis of brain RNA from mutant animals detected a 0.9 kb mutant transcript containing the PGK-neo insertion. Western blot analysis of several tissues from newborn homozygous mutant animals showed an absence of protein product. |
