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Allele : Vegfa<tm3.1Pec> vascular endothelial growth factor A; targeted mutation 3.1, Peter Carmeliet

Primary Identifier  MGI:2386593 Allele Type  Targeted
Gene  Vegfa Transmission  Germline
Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+> Is Recombinase  false
Is Wild Type  false
molecularNote  The floxed neo cassette was excised from Vegfatm3Pec by the in vivo expression of cre recombinase, leaving the isoform specific cDNA replacement intact. The resultant allele lacks exon 6 as well as splice sites and thereby produces a single isoform with intermediate solubility and receptor binding properties. The exclusive presence of this isoform was verified by quatitative RT-PCR.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • VEGF<164>,
  • VEGF<164>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

12 Publication categories