Primary Identifier | MGI:2386294 | Allele Type | Targeted |
Attribute String | Null/knockout, Reporter | Gene | H2-Oa |
Transmission | Germline | Strain of Origin | 129/Sv |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Sequence extending from nucleotide position 21 in exon 1 through position 861 in exon 5 was replaced with a cassette containing lacZ and neo via homologous recombination. Transcript was undetected in homozygous mutant mice via RT-PCR analysis of total spleen and thymis RNA. Homozygous mutant mice were shown to lack the endogenous protein via Western blot analysis of splenocytes. |