| Primary Identifier | MGI:2386300 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Gdf15 |
| Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | The gene was disrupted by replacement of exon 2 with a neomycin resistance cassette via homologous recombination. Exon 2 encodes the entire C-terminal domain of the protein. Homozygous mutant animals lack gene expression as demonstrated by Northern blot analysis of liver RNA using a probe to the C-terminal region of the gene. |
