Primary Identifier | MGI:2386313 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Krt6a |
Transmission | Germline | Strain of Origin | 129S7/SvEvBrd-Hprt1<b-m2> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The entire coding region of the gene was replaced with a neomycin resistance cassette, Hprt minigene, and loxP site. Homozygous mutant animals lacked gene expression and protein production as shown by RNase protection assay and Western blot analysis of whole skin samples, respectively. |