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Allele : Krt6a<tm1Der> keratin 6A; targeted mutation 1, Dennis R Roop

Primary Identifier  MGI:2386313 Allele Type  Targeted
Attribute String  Null/knockout Gene  Krt6a
Transmission  Germline Strain of Origin  129S7/SvEvBrd-Hprt1<b-m2>
Is Recombinase  false Is Wild Type  false
molecularNote  The entire coding region of the gene was replaced with a neomycin resistance cassette, Hprt minigene, and loxP site. Homozygous mutant animals lacked gene expression and protein production as shown by RNase protection assay and Western blot analysis of whole skin samples, respectively.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • MK6a<->,
  • MK6a<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories